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tirzepatide obesity nejm

tirzepatide obesity nejm SURMOUNT-1 (NEJM 2022) tested tirzepatide — a dual GIP/GLP-1 receptor agonist — in 2,539 adults with obesity and achieved up to 20.9% mean weight loss at the highest dose. 57% of participants

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Ms. Moon
Fort Morgan, US
★★★★★ 3
Not for narrow feet, very lightweight.
Size: 7.5, Color: Black
My feet are slightly narrow; these were not adjustable enough to make secure. Otherwise they are cute. The material feels kind of light, these were my first attempt at UGGs so I'm not sure if that's typical or an actual quality issue. Either way, they don't seem very durable but I can't imagine these are meant for roughing it.
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Reviewed in the United States on May 8, 2026
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sandra
West Palm Beach, US
★★★★★ 5
Decepcion
Size: 9.5, Color: Molasses
Excelentes sandalias supercomodas y ligeras quedan muy bien al pie, soy 9 y pedí 9.5 excelente
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Reviewed in the United States on May 28, 2026
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Pamela S. Brown
Lake Worth, US
★★★★★ 5
Great value
Size: 9.5, Color: Black
I absolutely adore these sandals. They are comfortable and super urban. Worth there value all the way around!
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Reviewed in the United States on March 24, 2026
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Lena Y.
Pawtucket, US
★★★★★ 5
Nice so far.
Size: 6.5, Color: Molasses
Comfy. They were tight the first day across the toes but as I've worn them a couple times they are loosening up. The sole is forming to my foot. These are very much like Doc Martin's from the early 2000s. Not sure about quality since I haven't had them for very long.
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Reviewed in the United States on March 27, 2026
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Just Carrie
San Leandro, US
★★★★★ 5
Comfortable
Size: 6, Color: Black
Great sandal! Fits great and comfy
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Reviewed in the United States on April 3, 2026

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