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Description
IL-28A/IFN-λ2 Protein, MouseProduct Specification Species Mouse Synonyms Interferon lambda 2; IFN lambda 2; Interleukin 28A; IL 28A; Accession Q4VK74 Amino Acid Sequence Asp20 Val193 Expression System E. coli Molecular Weight 20 kDa (Reducing) Purity >95% by SDS PAGE and HPLC. Endotoxin <0. 1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized Powder Storage Buffer 20mM Tris, 150mM NaCl, pH8. 0 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size
Product Specification
| Species | Mouse |
| Synonyms | Interferon lambda-2; IFN-lambda-2; Interleukin-28A; IL-28A; |
| Accession | Q4VK74 |
| Amino Acid Sequence | Asp20-Val193 |
| Expression System | E.coli |
| Molecular Weight | 20 kDa (Reducing) |
| Purity | >95% by SDS-PAGE and HPLC. |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | 20mM Tris, 150mM NaCl, pH8.0 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | Nat Immunol. 2003 Jan;4(1):63-8. |
Background
Interferon lambda 2 (IFN-λ2), also known as IL-28A, is a member of the type III interferon family, which also includes IFN-λ1 and IFN-λ3. IFN-λ2 plays a crucial role in the innate immune response to viral infections and has been shown to exhibit antiviral activity against a variety of viruses, including hepatitis C virus, influenza virus, and others. It signals through the IFN-λ receptor complex, leading to the activation of JAK-STAT signaling pathways and the induction of interferon-stimulated genes (ISGs) that contribute to the antiviral defense mechanisms. IFN-λ2 is primarily produced by immune cells, such as dendritic cells and macrophages, in response to viral stimuli and functions as a key mediator of the host's defense against viral pathogens.
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4.6 ★★★★★
Based on 7 reviews
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Product Reviews
★★★★★ 4
The series as a whole so far 5/25
Format: Kindle
I read reviews before going into this book and I don't agree with one of the more harsh ones on the main trigger she had. It is stated clearly in the forward and it wasn't as blase as it was made out to be. It definitely is touched on more and hasn't just been brushed off as the series goes
I definitely would recommend reading it. It's a good series just be for-warned
I like the series as a whole. The characters are awesome I adore the fmc shes cute and adorable but also a badass. Though there are a bunch of holes for her that I feel like just got left out.
The guys are interesting and shout out to yall for not making Gage a dragon. I'm tired of the broody ones who don't wanna talk aboit what they are being Dragons. Ki is my favorite
You can definitely tell if is written by 2 different people though because the phrasing just doesn't match up and wouldn't be something people that age says. And it flip flops between them.
I feel like there's substance without substance. We are 4 books in and we don't really know much back story on literally anyone more than right under surface deep.
There are definitely favorite MMCs which is kind of disappointing since some get shoved to the wayside. Specifically both of the best friends. They're basically useless and it's made obvious as the books go on. As well as all the men are ungodly self deprecating.
I enjoy the plot line for the most part like I said I enjoy the series its different and refreshing.
I do feel like the series is being dragged out though unfortunately. And the latest cliff hanger was just meh. So hopefully the next book is the last one.
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Reviewed in the United States on May 8, 2025
★★★★★ 5
Wow!
Format: Kindle
This book was awesome! Seraphina and her family have moved to a new town. Her family is a bit... odd. She grew up learning how to protect herself from people who might hurt her. Bloodshed is a daily occurrence with her brothers and parents during their practice sessions, and it’s all fun and games unless you need to hide a body.
Sera’s family is very close, and she’s been homeschooled most of her life. But in this new town she is going to start regular school as a senior at the local high school. Unfortunately, things at her school aren’t all they seem to be. Or perhaps more than they seem to be. Sera has her own demons to deal with, and she’s terrified her new friends will learn about her weird family and other issues and drop her like a rock. It turns out they have their own secrets as well.
This story ends on a bit of a cliffhanger and I can’t wait to read the next one! This book is well written and well edited. The heroine is spunky and has a great heart and wicked sense of humor.
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Reviewed in the United States on November 12, 2021
★★★★★ 5
Great start
Format: Kindle
I loved this book! It's funny but still deals with tough themes, like chronic illness, a serial killer on the loose, and a dash of self-harm. The guys are interesting and distinct, we don't know too much about them yet. It does end on a really terrible cliffhanger but on the bright side the next book is out and I believe the series is complete. I have enjoyed both of these authors separately and this is a great team up!
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Reviewed in the United States on May 2, 2025
★★★★★ 4
Fudge!
Format: Kindle
Titles aren’t my strong suit. Sorry not sorry.
That ending has me completely frustrated book two isn’t out yet. Just throwing that out there.
First thing first, this is a high school book where the lead is under 18. Yea yea she’s about month from being an adult, but I can’t say I would’ve even opened the file if I’d realized. It’s not a smut fest or anything, but there is sexual tension as each party figures out their emotions.
That being said, it’s a good book. There are some troubling parts, like how the supes come into their powers at 13, but most of those are dealt with in a way that makes sense. Kian is the exception. His whole arc pisses me off, especially since no one stepped in. Reflecting back on real world situations, ten or so years ago, I can see it happening, but it still makes me sick. Which, I’m sure was the whole damn point.
For the most part, Courting Darkness is a fun read. I found myself laughing along with most of the set up. By the time it started getting serious, I’d grown to like the characters enough it held an impact.
I’ll be adding book two to my list for when it comes out.
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Reviewed in the United States on March 8, 2022
★★★★★ 5
Intriguing
Format: Kindle
An intriguing story that played out slowly while introducing some unique characters. The story became quite fascinating to read as these same characters provided startling revelations to their lives. As their relationships evolve, more drama and mystery is revealed adding to my fascination. I can’t wait to read more.
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Reviewed in the United States on May 27, 2026
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