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Description
이소티논연질캡슐10 (Acne)1) , (, , ), 2) , , . 1 kg 0. 5 mg . 1 kg 0. 5~1. 0 mg , 2. 0 mg . 1 1, 1 2 . kg 120 mg , . 1 1624 , . 8 . : . 1 10 mg . : . . . 3) 100 4) , 10mg 5) 36 6) , (130C)
1) 효능,효과
다른 치료법으로 잘 치료되지 않는 중증의 여드름(결절성, 낭포성, 응괴성), 특히 체간 병변과 관련된 낭포성 및 응괴성 여드름
2) 용법,용량
이 약에 대한 치료효과 및 이상반응은 용량 의존적이므로, 환자의 증상 및 상태에 따라 용량을 적절히 조절한다.
○ 초기용량
이소트레티노인으로서 1일 체중 kg당 0.5 mg을 반응을 관찰하며 투여한다.
○ 유지용량
이 약으로서 1일 체중 kg당 0.5~1.0 mg을 투여하며, 중증의 여드름 환자에게는 2.0 mg까지 증량할 수 있다.
저용량의 경우는 1일 1회, 고용량의 경우는 1일 2회 분할하여 식사와 함께 복용한다.
치료과정마다 체중 kg당 120 mg의 누적용량은 증상의 호전율을 높이고, 재발률을 낮춘다. 치료기간은 1일 복용량에 따라 달라질 수 있으나 보통 16～24주가 소요되고, 치료중단 후에도 증상호전이 있을 수 있다. 따라서 증상이 재발될 경우 상기 치료과정을 반복하되 최소한 8주간의 휴약기간이 경과된 후 치료를 재개해야 한다.
○ 신부전환자 : 투여경험이 매우 제한적이다. 이 약을 투여할 경우 이 약으로서 1일 10 mg에서 시작하여 용량을 조절한다.
○ 불내약성인 환자 : 저용량으로 치료를 계속한다. 이 경우 치료기간이 연장되며 재발의 위험이 높아진다. 이런 환자의 경우 적응 가능한 최대 용량으로 치료를 계속하여 최적의 효과를 얻을 수 있다.
3) 포장단위
100캡슐/병
4) 성분,함량
이소트레티노인10mg
5) 사용기간
제조일로부터 36 개월
6) 보관방법
차광밀폐용기, 실온(1∼30°C)보관
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4.2 ★★★★★
Based on 1156 reviews
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Product Reviews
★★★★★ 5
Angels and the Fallen — Breathtaking Start
Format: Kindle
This book was EVERYTHING I expected it to be and more. Leave to R.L. Caulder and M. Sinclair to give us yet another amazing book!
Kieran and her guys hooked me from the very beginning and did not let go. Found family is one of my favorite tropes and it was done so well in this book. Couple that along with an FMC trying to find her place in the world and I was practically drooling over this book. The world building, the conflict, the wyverin sidekick — it all was done so well that it felt fresh and real.
Each love interest felt real and unique in their own ways. I felt connected to each one and like they were truly different people. I love that so much in a book and these two authors never miss with their love interests.
Multi POV, Reverse harem, who did this to you, and a magical world highlighting the angels and the fallen. This book has everything and it does it so well.
Big thank you to R.L. Caulder and M. Sinclair for the arc copy! I cannot wait for book 2!
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Reviewed in the United States on February 20, 2024
★★★★★ 4
A new take 🤔
Format: Kindle
I’m not going to go into what this book is about — by now you e already read the synopsis and have an idea — but I will give a couple of insights.
Definitely a different take on angels and their fall; I like it. This is an interesting start to a new series - YES, this does end on a cliffhanger so be prepared for that. I’m eager for the next book (and hopefully the last in this series — sometimes the author(s) will switch it up depending on how the story flows for them) in this series.
I’m hoping that a certain male character redeems himself because he’s a dick that will make the meaning of mixed signals jealous lol.
You ever watch that old movie — I think it’s call Mommy Dearest? — yea, let’s switch that up to daddy. That man would make a perfect husband to mommy dearest.
I recommend this book because while these authors are well known for their cliffhangers, they are also well known for putting out good stories.
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Reviewed in the United States on February 19, 2024
★★★★★ 3
Liked it
Format: Kindle
I liked the worlds and the characters. The prophesy is confusing in that I would think, since all worlds ore on a path to destruction, the angels would want their world to be saved. I am sure there is more evil that will be revealed as the series proceeds. I dislike a prolonged “poor little me” trope and the main character has moved past that, thankfully, and began to show a fierce attitude as the novel progressed. The last portion of the novel had some great action. It’s worth reading, just be patient with a slow start.
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Reviewed in the United States on February 14, 2024
★★★★★ 5
Unexpectedly emotional and packed with action!
Format: Kindle
Why do I suddenly want nothing more than a tiny wyvern to snuggle with?! It’s adorable and I absolutely love all of those moments! Wings of Stars was everything I’ve come expect from this powerful author duo. The fact that it’s written by two different people is completely transparent to the reader and they’ve brought us another world and characters that we’re all emotionally connected to and fully invested in! The injustice that we see from Alfemir in the many forms in which it comes is infuriating and makes me desperate for the conclusion of the story so they can all get what’s coming to them! I love all the guys right now, with one exception, and if you’re read it, you know exactly who I’m talking about. Bastian is hilarious - he was the comedic relief through an otherwise quite serious story. My heart bleeds for him and I can’t wait to see how he progresses through the series. Parts of Wings of Stars were unexpectedly emotional and of course I was left with my jaw on the floor at that cliffhanger! Next, please!
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Reviewed in the United States on October 18, 2025
★★★★★ 5
Niz !!!
Format: Kindle
First, let me say that I love both of these authors. I have been hooked by both ever since I discovered their writings, and I follow their social media groups closely. This book did not disappoint. Sure, there are several questions that I have, a couple of times I went huh (which I won't get into because I do not want to offer any spoilers) and I hated the cliff hanger lol, but I cannot lie and say I didn't love the book, because I did. The twist on angels was new and fresh, even though that is part of my questions. The beginning and ending were the better parts, the middle was needed but sorta bogged a little. Kieran was confusing but relatable. Niz is BY FAR the best character of the book, love NIZ. For me, Bastian is a close second, always loved the crazy ones. The other men were good, but Steele gets on my nerves and as of right now, IMO, he doesn't belong, but we will see how that goes. I have lots of questions, but this was an excellent start to a new series and I cannot wait for the next book. Highly recommend
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Reviewed in the United States on February 21, 2024