SKU: 44307856515

24-Hour Retinol 5% Serum with Apple Stem Cell | Anti-Ageing & Skin Renewal | Ammuri Beauty

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Description

24-Hour Retinol 5% Serum with Apple Stem Cell | Anti-Ageing & Skin Renewal | Ammuri BeautyRenewal That Works Around The Clock The Ammuri 24 Hour Retinol 5% Serum with Apple Stem Cell is a high performance anti ageing treatment formulated for those ready to take their skincare seriously. Combining one of dermatology's most studied actives Retinol with the regenerative potential of Apple Stem Cell technology, this serum works continuously to support skin renewal, visibly reduce the signs of ageing, and restore a firmer, more youthful looking

Renewal That Works Around The Clock

The Ammuri 24-Hour Retinol 5% Serum with Apple Stem Cell is a high-performance anti-ageing treatment formulated for those ready to take their skincare seriously. Combining one of dermatology's most studied actives — Retinol — with the regenerative potential of Apple Stem Cell technology, this serum works continuously to support skin renewal, visibly reduce the signs of ageing, and restore a firmer, more youthful-looking complexion.

This is not a quick fix. It is a long-term investment in your skin's future.


Key Benefits

  • Visibly reduces the appearance of fine lines and wrinkles with consistent use
  • Supports skin cell renewal for a smoother, more refined texture
  • Helps improve skin firmness and elasticity over time
  • Promotes a more even skin tone and reduced appearance of dark spots
  • Provides 24-hour hydration support without heaviness
  • Enhances overall radiance and skin clarity

Who This Serum Is For

Formulated for those experiencing:

  • Early to established fine lines and wrinkles
  • Loss of skin firmness or elasticity
  • Uneven skin texture or rough surface
  • Dullness and lack of radiance
  • Dark spots or uneven skin tone related to ageing or sun exposure
  • Those ready to introduce a clinically studied anti-ageing active into their routine

Recommended for ages 30 and above, or earlier for those with advanced sun exposure history. Not recommended during pregnancy or breastfeeding.


Ingredient Spotlight

Retinol 5%
One of the most extensively studied ingredients in skincare, Retinol is a Vitamin A derivative that accelerates skin cell turnover, stimulates collagen production, and visibly reduces the appearance of fine lines, wrinkles, and uneven skin tone. At 5%, this formulation delivers meaningful results while remaining suitable for regular use when introduced gradually.

Apple Stem Cell Extract
Derived from a rare Swiss apple variety, Apple Stem Cell Extract is used in skincare for its ability to support the longevity of skin stem cells and promote a more youthful cellular environment. It works synergistically with Retinol to enhance the skin's natural renewal processes.

Hyaluronic Acid
A powerful humectant that draws moisture into the skin and helps retain it throughout the day and night. Its inclusion counterbalances the potential drying effect of Retinol, keeping the skin comfortable and hydrated throughout the renewal process.

Niacinamide (Vitamin B3)
Supports the skin barrier, minimises pore appearance, and helps reduce redness and uneven tone. Niacinamide works in harmony with Retinol to enhance results while improving overall skin tolerance.

Peptides
Short-chain amino acids that signal the skin to produce more collagen and elastin. Peptides complement Retinol's action by supporting structural skin proteins, contributing to improved firmness and resilience over time.


Texture & Feel

The 24-Hour Retinol Serum has a smooth, fluid texture that absorbs quickly and evenly across the skin. It does not pill under moisturiser and leaves no greasy residue. Designed for evening use as the primary application, it can also be used in the morning when followed by SPF 50.


How To Use

Evening Routine (PM) — Primary Application

  1. Double cleanse to remove SPF and impurities
  2. Apply toner or essence if used
  3. Dispense 3–4 drops onto fingertips
  4. Press gently into skin — do not rub or drag
  5. Follow with a nourishing night moisturiser or facial oil

Morning Routine (AM) — Optional

  1. Cleanse and tone
  2. Apply serum
  3. Follow with moisturiser
  4. Finish with SPF 50 — mandatory when using Retinol

If new to Retinol, begin with evening use only, 3 nights per week. Gradually increase to nightly use as your skin builds tolerance over 4–6 weeks.


Results Timeline

Weeks 1–2: Skin may experience a brief adjustment period — mild dryness or sensitivity is normal as cell turnover increases. Hydration is key during this phase.

Weeks 3–4: Skin texture begins to feel smoother and more refined. Early improvement in radiance and tone becomes visible.

Weeks 6–8: Visible reduction in fine lines and improved skin firmness. Skin tone appears more even and luminous.

Long-term consistency: With continued use, collagen support compounds and skin renewal deepens. The most significant anti-ageing results are seen at the 3–6 month mark and beyond.


Complete Your Anti-Ageing Routine

For optimal results, pair with:

  • Ammuri Peptide Anti-Ageing Serum — use in the morning to complement Retinol's evening action with daytime collagen support
  • Ammuri Vitamin C Day Cream SPF 50 — essential daily protection that shields skin from UV damage and prevents further signs of ageing

Never skip SPF when using Retinol. UV exposure without protection will counteract your results and increase sensitivity.


Frequently Asked Questions

Is 5% Retinol suitable for beginners?
If you are new to Retinol, we recommend starting slowly — use every third evening for the first two weeks, then every other evening, building to nightly use over 4–6 weeks. This allows your skin to build tolerance comfortably.

Can I use this with other actives?
Retinol pairs well with Hyaluronic Acid and Peptides. Avoid using alongside AHAs, BHAs, or Vitamin C in the same application to prevent irritation. Use Vitamin C in the morning and Retinol in the evening.

Why is SPF so important with Retinol?
Retinol increases the rate of skin cell turnover, which makes the skin more sensitive to UV radiation. Without daily SPF 50, you risk increased sun damage, sensitivity, and reversal of your anti-ageing progress.

Can I use this during pregnancy or breastfeeding?
No. Retinol is not recommended during pregnancy or breastfeeding. Please consult your healthcare provider for suitable alternatives during this time.

How long until I see real results?
Most customers notice improved texture and radiance from weeks 3–4. Visible reduction in fine lines typically becomes apparent from week 6–8 with consistent use. The most transformative results come with 3–6 months of commitment.


Our Promise

  • 🇬🇧 Developed in the UK
  • 🐰 Cruelty-free — never tested on animals
  • 🔬 Science-backed formulation with clinically studied actives
  • 🌿 Free from unnecessary fillers and harsh irritants
  • ✨ Dermatologist-inspired — formulated with skin health at its core

Ammuri Beauty is built on the belief that effective skincare should be purposeful, transparent, and honest. Every product is developed with integrity — no overclaiming, no shortcuts, no compromise.

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 44307856515

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T
The Beauty Chronicles
Birmingham, US
★★★★★ 5
MICRONEEDLING IS MY SKIN’S SECRET WEAPON!!!
Microneedling completely transformed my skin. Of every treatment I have ever tried, this one has made the biggest difference in texture, glow, and overall refinement. After years of paying for appointments, I decided to learn proper technique and invest in a Dr. Pen device for at home use, and I truly have never looked back. Needle Options and Coverage: I typically use a 16 pin cartridge, so I am excited to incorporate the 36 pin into my routine. The wider pin configuration allows for broader coverage, which makes it especially useful for larger areas of the face and even the body. It gives me more versatility in my treatments. Compatibility and Value: It is such a relief to find cartridges that are compatible with my Dr. Pen device right here on Amazon. The price point is very reasonable, especially compared to professional treatment costs. Having reliable, accessible replacements makes maintaining my routine so much easier. Excellent value for the money. Final Thoughts: Convenient, affordable, and a great addition to my microneedling routine… I love having professional level tools within reach… and my skin continues to thank me for it…
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Reviewed in the United States on February 20, 2026
M
Me
Charlottesville, US
★★★★★ 5
A long, HONEST & detail filled review (with usage tips) from a skincare junkie.
These cartridges arrived super fast (with enough time to spare for a quick face sesh before the holidays!). The lot of 12 was packed in a cellophane/paper bag (the basic, unlabeled sterilization bags) that was sealed shut. The cartridges themselves are all separately packaged (in smaller plastic/paper sterilization bags), each one was properly sealed shut, ensuring sterilization. The individual bags have an illustration of the cartridge and are labeled as “36 NEEDLE” . There are photos of and all the different size needle patterns as well. Each package contains a proper lot #, manufacture date (10/10/25) and expiration date (10/09/2028) along with the info that the disposable tips were sterilized with non-pyrogen EO Gas. Not a single package was damaged or open and all contained the proper cartridge inside. I was VERY happy when I removed one of the cartridges and saw that it (they all) have the protective cap/cover inside the tube/over the needles. Not only is that more sanitary and keeps the needles protected in the event the spring is pushed, but it's also a dead giveaway for spotting bad/bootleg cartridges (as they typically don't come with the cap). While these might not be brand name, they definitely aren't bootleg quality! These are nearly identical to the cartridges I order directly from Dr. Pen. They are the same size and shape, with the color of the plastic tubing being the only slight difference. The 36 needle pattern is legit, with the long row of 10 needles in the center, a row above and below that with 8 needles and the rows on the top and bottom containing 5 needles each. They are perfectly spaced and staggered. The cartridges fit my M7S perfect- nice and snug with no wiggling or looseness. The silicone membrane keeps your pen clean and hygienic and the spring system provides smooth, continuous movement without the needles getting stuck or punching jerky. The needles themselves are very fine and they are nice and sharp. I am extremely sensitive to anything other than medical grade stainless or titanium (I know immediately when I'm using something that's not that!) and I haven't had a single issue with these. Considering 10 brand name cartridges are $40, getting 12 of these that look and function almost identically for $25 is a steal. With no minimum spend for shipping and quick arrival time, I know I'll be buying these again! ⭐️TIPS FOR USING THE 36 NEEDLE CARTRIDGES⭐️ These cartridges are perfect for wrinkles and fine lines, large pores, pigmentation, increasing firmness as well as hydration (after using these, your products sink deep down in the skin- quick. It's great!). *For lines and wrinkles on the face and neck, you want a depth of 1.5 - 2.0mm (with a max of 1.5 for the glabellar lines or the 11's). For wrinkles around the lips, 0.5 - 1.5mm *If you are working on your pores, 0.5 - 1.0mm depth *Uneven pigmentation, 0.5 - 1.5mm depth and 1.0 - 2.0mm depth for sun spots specifically. *For firmer, tighter skin and skin laxity, 1.5 - 2.0mm These are just some general depth guidelines I use with these cartridges. I am not an aesthetician, but I am a total skincare junkie that has been microneedling myself for the past 15 years. As always, do your own research, especially because different areas around the face may require a shallower depth. If you are uncomfortable, then adjust the depth for your comfort. Finally, remember to clean your skin, hands and pen throughly before microneedling and work in a clean environment too. You don't want to introduce any bacteria or germs 2mm down (or even .5mm down) in your dermis. Also, these are single use cartridges and they are very affordable, so don't try to clean and reuse them (that's just asking for trouble!) Instead, toss and replace!
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Reviewed in the United States on December 23, 2025
I
Verified Purchase
Iviana Beauty
Cuba, US
★★★★★ 1
No es para Dr Pen M8
No le sirve al Dr Pen M8
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 19, 2026
C
Customer review
Battle Creek, US
★★★★★ 5
For larger size areas
Top quality with stainless steel material. Using 36 pins which sturdy pins. It fits well on M8 and easy to use. Because of the size it works a bit tougher/ harder providing deeper penetration. Because of the amount of pins these are for larger sized areas leaving this more for moderate to experts to be able to use this efficiently and effectively. Good value for the money
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Reviewed in the United States on January 13, 2026
E
Esbe Hennessy
Grantham, US
★★★★★ 5
Works just as well as the OG, but for much less
This is a perfect and less costly way to get microneedling cartridges for my Dr. Pen M8. They fit perfectly and work just as well. They come with all kinds of precautions taken to keep them sterile, which is very important with something meant to reach down into your skin. The pins are just like the originals and honestly I can't feel any difference when using it. There's no need to pay more for name brand when these work just as well. I'm always a bit cautious because so many off brands aren't just cheap in price, but in quality. Not these, they're the real deal. You can save money and get replacement cartridges that will do a great job.
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Reviewed in the United States on December 28, 2025

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